Effect of short-term systemic glucocorticoid treatment on human nasal mediator release after antigen challenge

The effect of systemic glucocorticoid treatment on early- and late-phase nasal allergic reactions after allergen challenge was determined in a double-blind, cross-over study in 13 allergic individuals. The subjects were pretreated for 2 d before challenge with 60 mg prednisone per day or a matching...

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Veröffentlicht in:	The Journal of clinical investigation 1987-10, Vol.80 (4), p.957-961
Hauptverfasser:	PIPKORN, U, PROUD, D, LICHTENSTEIN, L. M, SCHLEIMER, R. P, PETERS, S. P, ADKINSON, N. F, KAGEY-SOBOTKA, A, NORMAN, P. S, NACLERIO, R. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Aerosols Biological and medical sciences Chromatography, High Pressure Liquid Double-Blind Method Histamine - analysis Histamine Release Humans Hypersensitivity - drug therapy Kinins - analysis Leukocyte Count Medical sciences Nasal Mucosa - drug effects Nasal Mucosa - secretion Peptide Hydrolases - analysis Pharmacology. Drug treatments Pollen Prednisone - therapeutic use Prostaglandin D2 Prostaglandins D - analysis Random Allocation Respiratory system Serum Albumin - analysis Sneezing - drug effects SRS-A - analysis
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