Improved sleep quality in older adults with insomnia reduces biomarkers of disease risk: Pilot results from a randomized controlled comparative efficacy trial

Improved sleep quality in older adults with insomnia reduces biomarkers of disease risk: Pilot results from a randomized controlled comparative efficacy trial

Highlights • Individuals starting the trial with high multisystem biological risk and assigned to CBT or TCC showed improvements in risk scores after 1 year. • Findings suggest that improving sleep quality has the potential to reduce the risk of chronic disease in older adults with sleep disturbance...

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Veröffentlicht in:Psychoneuroendocrinology 2015-05, Vol.55, p.184-192
Hauptverfasser: Carroll, Judith E, Seeman, Teresa E, Olmstead, Richard, Melendez, Gerson, Sadakane, Ryan, Bootzin, Richard, Nicassio, Perry, Irwin, Michael R
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Allostasis
Allostatic load
Biomarkers - metabolism
Blood Glucose - metabolism
C-Reactive Protein - metabolism
Cardiovascular Diseases - metabolism
Cholesterol, HDL - metabolism
Cholesterol, LDL - metabolism
ClinicalTrials.gov: NCT00280020, Behavioral Treatment of Insomnia in Aging
Cognitive Behavioral Therapy - methods
Diabetes Mellitus - metabolism
Disease risk
Endocrinology & Metabolism
Female
Fibrinogen - metabolism
Glycated Hemoglobin - metabolism
Humans
Insomnia
Insulin - metabolism
Intervention
Male
Middle Aged
Multisystem
Patient Education as Topic - methods
Pilot Projects
Psychiatry
Sleep
Sleep Initiation and Maintenance Disorders - metabolism
Sleep Initiation and Maintenance Disorders - therapy
Tai Ji - methods
Treatment Outcome
Triglycerides - metabolism
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Beschreibung
Zusammenfassung:Highlights • Individuals starting the trial with high multisystem biological risk and assigned to CBT or TCC showed improvements in risk scores after 1 year. • Findings suggest that improving sleep quality has the potential to reduce the risk of chronic disease in older adults with sleep disturbances. • This is the first study to report that a treatment trial for insomnia in older adults impacts clinical markers of risk for disease.
ISSN:0306-4530
1873-3360
DOI:10.1016/j.psyneuen.2015.02.010