Biocontainment of genetically modified organisms by synthetic protein design

Genetically modified organisms (GMOs) are increasingly deployed at large scales and in open environments. Genetic biocontainment strategies are needed to prevent unintended proliferation of GMOs in natural ecosystems. Existing biocontainment methods are insufficient because they impose evolutionary...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2015-02, Vol.518 (7537), p.55-60
Hauptverfasser:	Mandell, Daniel J., Lajoie, Marc J., Mee, Michael T., Takeuchi, Ryo, Kuznetsov, Gleb, Norville, Julie E., Gregg, Christopher J., Stoddard, Barry L., Church, George M.
Format:	Artikel
Sprache:	eng
Schlagworte:	101/58 119/118 13/31 38/1 38/77 42/70 45/23 631/114 631/181/735 631/208 631/61 Amino acids Amino Acids - chemistry Amino Acids - metabolism BASIC BIOLOGICAL SCIENCES Biological Evolution biotechnology Codon - genetics computational biology and bioinformatics Containment of Biohazards - methods Design E coli Ecosystem Escherichia coli - enzymology Escherichia coli - genetics Escherichia coli - growth & development Escherichia coli - metabolism Escherichia coli Proteins - biosynthesis Escherichia coli Proteins - genetics Escherichia coli Proteins - metabolism Gene Transfer, Horizontal - genetics Genes Genes, Essential - genetics Genetic Code - genetics Genetic engineering Genetic Engineering - methods Genetically modified organisms genetics Humanities and Social Sciences Metabolites Microbial Viability - genetics molecular evolution multidisciplinary Mutation Mutation - genetics Organisms Organisms, Genetically Modified - genetics Organisms, Genetically Modified - metabolism Proteins Safety Science Selection, Genetic Synthetic Biology - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!