Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals

NK cells contribute to postvaccination immune responses after activation by IL-2 from Ag-specific memory T cells or by cross-linking of the low-affinity IgG receptor, CD16, by Ag-Ab immune complexes. Sensitivity of NK cells to these signals from the adaptive immune system is heterogeneous and influe...

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Veröffentlicht in:The Journal of immunology (1950) 2015-05, Vol.194 (10), p.4657-4667
Hauptverfasser: Nielsen, Carolyn M, White, Matthew J, Bottomley, Christian, Lusa, Chiara, Rodríguez-Galán, Ana, Turner, Scarlett E G, Goodier, Martin R, Riley, Eleanor M
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Sprache:eng
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