Adipose-derived mesenchymal stromal cells modulate tendon fibroblast responses to macrophage-induced inflammation in vitro

Macrophage-driven inflammation is a key feature of the early period following tendon repair, but excessive inflammation has been associated with poor clinical outcomes. Modulation of the inflammatory environment using molecular or cellular treatments may provide a means to enhance tendon healing. To...

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Veröffentlicht in:	Stem cell research & therapy 2015-04, Vol.6 (1), p.74-74, Article 74
Hauptverfasser:	Manning, Cionne N, Martel, Catherine, Sakiyama-Elbert, Shelly E, Silva, Matthew J, Shah, Shivam, Gelberman, Richard H, Thomopoulos, Stavros
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Analysis Animals Cell Differentiation Cell Survival - immunology Cells, Cultured Computer software industry Cytokines - secretion Fibroblasts - cytology Gene expression Health aspects Inflammation Inflammation - immunology Innovations Interleukin-1beta - pharmacology Interleukins Macrophages Macrophages - immunology Male Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - physiology Mice Mice, Inbred C57BL Stem cells Tendons - cytology Wound Healing - physiology
Online-Zugang:	Volltext
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