Nuclear reprogramming with a non-integrating human RNA virus

Advances in the field of stem cells have led to novel avenues for generating induced pluripotent stem cells (iPSCs) from differentiated somatic cells. iPSCs are typically obtained by the introduction of four factors--OCT4, SOX2, KLF4, and cMYC--via integrating vectors. Here, we report the feasibilit...

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Veröffentlicht in:	Stem cell research & therapy 2015-03, Vol.6 (1), p.48-48, Article 48
Hauptverfasser:	Driscoll, Christopher B, Tonne, Jason M, El Khatib, Moustafa, Cattaneo, Roberto, Ikeda, Yasuhiro, Devaux, Patricia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Surface - genetics Biomarkers Cell Line Cellular Reprogramming - genetics Cellular Reprogramming - physiology Cercopithecus aethiops Fibroblasts - cytology Fluorescence Foreskin - cytology Genetic aspects Genetic transcription Genetic vectors HEK293 Cells Homeodomain Proteins - genetics Humans Induced Pluripotent Stem Cells - cytology Kruppel-Like Transcription Factors - biosynthesis Kruppel-Like Transcription Factors - genetics Male Measles Measles virus - genetics Medical equipment and supplies industry Medical test kit industry Mice Mice, SCID Myocytes, Cardiac - cytology Nanog Homeobox Protein Octamer Transcription Factor-3 - biosynthesis Octamer Transcription Factor-3 - genetics Proteoglycans - genetics Proto-Oncogene Proteins c-myc - biosynthesis Proto-Oncogene Proteins c-myc - genetics RNA Skin - cytology SOXB1 Transcription Factors - biosynthesis SOXB1 Transcription Factors - genetics Stage-Specific Embryonic Antigens - genetics Stem cells Vaccines Vero Cells
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