MRI in Leber's hereditary optic neuropathy: the relationship to multiple sclerosis

Background Leber's hereditary optic neuropathy (LHON) and a multiple sclerosis (MS)-like illness appear to coexist 50 times more frequently than would be expected by chance. This association of LHON and MS (LMS) raises an important question about whether there could be a common pathophysiologic...

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Veröffentlicht in:	Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2015-05, Vol.86 (5), p.537-542
Hauptverfasser:	Matthews, Lucy, Enzinger, Christian, Fazekas, Franz, Rovira, Alex, Ciccarelli, Olga, Dotti, Maria Teresa, Filippi, Massimo, Frederiksen, Jette L, Giorgio, Antonio, Küker, Wilhelm, Lukas, Carsten, Rocca, Maria A, De Stefano, Nicola, Toosy, Ahmed, Yousry, Tarek, Palace, Jacqueline
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain research Female Humans Magnetic Resonance Imaging Male Middle Aged Multiple Sclerosis Multiple Sclerosis, Relapsing-Remitting - complications Multiple Sclerosis, Relapsing-Remitting - pathology Mutation Neuroimaging Optic Atrophy, Hereditary, Leber - complications Optic Atrophy, Hereditary, Leber - pathology Sex Factors Single-Blind Method Volumetric analysis White Matter - pathology Young Adult
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