Using isoelectric point to determine the pH for initial protein crystallization trials

The identification of suitable conditions for crystallization is a rate-limiting step in protein structure determination. The pH of an experiment is an important parameter and has the potential to be used in data-mining studies to help reduce the number of crystallization trials required. However, t...

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Veröffentlicht in:	Bioinformatics 2015-05, Vol.31 (9), p.1444-1451
Hauptverfasser:	Kirkwood, Jobie, Hargreaves, David, O'Keefe, Simon, Wilson, Julie
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Buffer solutions Buffers Crystallization Estimates Hydrogen-Ion Concentration Isoelectric Point Mathematical models Original Papers Proteins Proteins - chemistry
Online-Zugang:	Volltext
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