Protein kinase Cδ promotes proliferation and induces malignant transformation in skeletal muscle

In this paper, we investigated the isoform‐specific roles of certain protein kinase C (PKC) isoforms in the regulation of skeletal muscle growth. Here, we provide the first intriguing functional evidence that nPKCδ (originally described as an inhibitor of proliferation in various cells types) is a k...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular and molecular medicine 2015-02, Vol.19 (2), p.396-407
Hauptverfasser:	Czifra, Gabriella, Szöllősi, Attila, Nagy, Zsuzsanna, Boros, Miklós, Juhász, István, Kiss, Andrea, Erdődi, Ferenc, Szabó, Tamás, Kovács, Ilona, Török, Miklós, Kovács, László, Blumberg, Peter M., Bíró, Tamás
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis C2C12 myoblasts Cell Line, Tumor Cell proliferation Cell Proliferation - physiology Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Cells, Cultured differentiation Experiments Humans Hypotheses Immunodeficiency Immunoglobulins Insulin Isoforms Kinases Mice Muscle, Skeletal - metabolism Muscles Musculoskeletal system nPKCδ Original Penicillin Phosphorylation PKC isoenzymes proliferation Protein kinase C Protein Kinase C-delta - metabolism Proteins recombinant overexpression Rhabdomyosarcoma Skeletal muscle Tumors tumourigenesis Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!