The involvement of follistatin-like protein 1 in osteoarthritis by elevating NF-κB-mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation

Our previous work has revealed that expression of follistatin-like protein 1 (FSTL1) is elevated in the synovial tissues from osteoarthritis (OA) patients. The aim of this study was to elucidate the underlying molecular mechanisms by which FSTL1 plays a role in the pathogenesis of OA. Cultured fibro...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Arthritis research & therapy 2015-04, Vol.17 (1), p.91-91, Article 91
Hauptverfasser:	Ni, Su, Miao, Kaisong, Zhou, Xianju, Xu, Nanwei, Li, Chenkai, Zhu, Ruixia, Sun, Rongbin, Wang, Yuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Blotting, Western Case-Control Studies Cell Proliferation Cells, Cultured Cytokines - metabolism Disease Progression Enzyme-Linked Immunosorbent Assay Female Fibroblasts - cytology Fibroblasts - drug effects Follistatin - pharmacology Follistatin-Related Proteins - metabolism Humans Inflammation Mediators - metabolism Interleukin-6 - metabolism Male Middle Aged NF-kappa B - metabolism Osteoarthritis - blood Osteoarthritis - physiopathology Real-Time Polymerase Chain Reaction Reference Values Synovial Membrane - cytology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!