Capillary electrophoresis for the analysis of the effect of sample preparation on early stages of Aβ1-40 aggregation

Aggregation of the amyloid‐β protein (Aβ) contributes to the neurodegeneration characteristic of Alzheimer's disease. Of particular importance are the early stages of aggregation, which involve the formation of soluble oligomers and protofibrils. In these studies, we demonstrate the potential f...

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Veröffentlicht in:	Electrophoresis 2014-07, Vol.35 (12-13), p.1814-1820
Hauptverfasser:	Pryor, N. Elizabeth, Moss, Melissa A., Hestekin, Christa N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyloid beta Amyloid beta-Peptides - chemistry Capillary electrophoresis Dot blot Electrophoresis, Capillary - methods Humans Immunoblotting Oligomer Peptide Fragments - chemistry Protein Aggregates Recombinant Proteins - chemistry
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