Tumor immune remodeling by TGFβ inhibition improves the efficacy of radiation therapy

The tumor immune environment has been linked to prognosis in patients with a range of malignancies. Recently, we demonstrated in pre-clinical models that modifying the tumor immune environment using a small-molecule inhibitor of TGFb significantly improved outcome to subsequent radiation therapy. Th...

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Veröffentlicht in:	Oncoimmunology 2015-03, Vol.4 (3), p.e955696-e955696
Hauptverfasser:	Young, Kristina H, Gough, Michael J, Crittenden, Marka
Format:	Artikel
Sprache:	eng
Schlagworte:	Author's View colorectal immunoscore immunotherapy pancreas radiation TGFβ
Online-Zugang:	Volltext
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