Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis

Objectives: To review and evaluate the efficacy and safety of tian jiu therapy on san fu tian for adults with asthma. Methods: A literature search through August 31, 2013, was done to identify comparative studies evaluating effective rate, pulmonary function, immune response, recurrence rate, qualit...

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Veröffentlicht in:The journal of alternative and complementary medicine (New York, N.Y.) N.Y.), 2015-04, Vol.21 (4), p.2-207
Hauptverfasser: Chan, Clara W.C., Lee, Sau Chun, Lo, Kwai Ching, Wong, Hei Kiu, Li, Lei
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container_issue 4
container_start_page 2
container_title The journal of alternative and complementary medicine (New York, N.Y.)
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creator Chan, Clara W.C.
Lee, Sau Chun
Lo, Kwai Ching
Wong, Hei Kiu
Li, Lei
description Objectives: To review and evaluate the efficacy and safety of tian jiu therapy on san fu tian for adults with asthma. Methods: A literature search through August 31, 2013, was done to identify comparative studies evaluating effective rate, pulmonary function, immune response, recurrence rate, quality of life, and adverse events. The Cochrane Library, PubMed, EMBASE, and Chinese National Knowledge Infrastructure were searched; only randomized controlled trials with treatment groups using tian jiu therapy were included. Cochrane Collaboration's risk of bias tool and Review Manager software, version 5.2, were used for the data synthesis. Results: Six studies involving 657 patients were identified. tian jiu therapy was more effective than the control intervention (odds ratio [OR], 3.51; 95% confidence interval [CI], 2.05–6.00; p
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Methods: A literature search through August 31, 2013, was done to identify comparative studies evaluating effective rate, pulmonary function, immune response, recurrence rate, quality of life, and adverse events. The Cochrane Library, PubMed, EMBASE, and Chinese National Knowledge Infrastructure were searched; only randomized controlled trials with treatment groups using tian jiu therapy were included. Cochrane Collaboration's risk of bias tool and Review Manager software, version 5.2, were used for the data synthesis. Results: Six studies involving 657 patients were identified. tian jiu therapy was more effective than the control intervention (odds ratio [OR], 3.51; 95% confidence interval [CI], 2.05–6.00; p &lt;0.00001; I 2 =18%). The treatment group had a bigger decrease in IgE level (standard mean difference [SMD], −1.40; 95% CI, −2.18 to −0.63; p =0.0004; I 2 =85%) and Eosinophil (Eos) level (SMD, −4.26; 95% CI, −6.28 to −2.23; p &lt;0.00001; I 2 =91%) compared with the control group. Included studies had a high risk of bias. Few adverse effects were reported in the included studies, and no serious adverse responses occurred. Adverse effects did not result in any dropouts. Conclusions: All studies indicated that tian jiu therapy has a positive effect on adults with asthma and that it is relatively safe because of its noninvasive nature. However, the limitations of the research design of the existing studies resulted in high risk of bias. More randomized controlled trials of better methodologic quality are needed to further confirm efficacy and safety of this therapy.</description><identifier>ISSN: 1075-5535</identifier><identifier>EISSN: 1557-7708</identifier><identifier>DOI: 10.1089/acm.2014.0009</identifier><identifier>PMID: 25759906</identifier><language>eng</language><publisher>United States: Mary Ann Liebert, Inc</publisher><subject>Acupuncture Points ; Acupuncture Therapy ; Adult ; Asthma - blood ; Asthma - drug therapy ; Asthma - therapy ; Drugs, Chinese Herbal - pharmacology ; Drugs, Chinese Herbal - therapeutic use ; Eosinophils - metabolism ; Humans ; Immunoglobulin E - blood ; Odds Ratio ; Phytotherapy ; Review ; Review Articles</subject><ispartof>The journal of alternative and complementary medicine (New York, N.Y.), 2015-04, Vol.21 (4), p.2-207</ispartof><rights>2015, Mary Ann Liebert, Inc.</rights><rights>Copyright 2015, Mary Ann Liebert, Inc. 2015</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-99ffd37839d4978559dc64bc1c5b2246b732e465f878c73a82a68318c15a39693</citedby><cites>FETCH-LOGICAL-c431t-99ffd37839d4978559dc64bc1c5b2246b732e465f878c73a82a68318c15a39693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25759906$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chan, Clara W.C.</creatorcontrib><creatorcontrib>Lee, Sau Chun</creatorcontrib><creatorcontrib>Lo, Kwai Ching</creatorcontrib><creatorcontrib>Wong, Hei Kiu</creatorcontrib><creatorcontrib>Li, Lei</creatorcontrib><title>Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis</title><title>The journal of alternative and complementary medicine (New York, N.Y.)</title><addtitle>J Altern Complement Med</addtitle><description>Objectives: To review and evaluate the efficacy and safety of tian jiu therapy on san fu tian for adults with asthma. Methods: A literature search through August 31, 2013, was done to identify comparative studies evaluating effective rate, pulmonary function, immune response, recurrence rate, quality of life, and adverse events. The Cochrane Library, PubMed, EMBASE, and Chinese National Knowledge Infrastructure were searched; only randomized controlled trials with treatment groups using tian jiu therapy were included. Cochrane Collaboration's risk of bias tool and Review Manager software, version 5.2, were used for the data synthesis. Results: Six studies involving 657 patients were identified. tian jiu therapy was more effective than the control intervention (odds ratio [OR], 3.51; 95% confidence interval [CI], 2.05–6.00; p &lt;0.00001; I 2 =18%). The treatment group had a bigger decrease in IgE level (standard mean difference [SMD], −1.40; 95% CI, −2.18 to −0.63; p =0.0004; I 2 =85%) and Eosinophil (Eos) level (SMD, −4.26; 95% CI, −6.28 to −2.23; p &lt;0.00001; I 2 =91%) compared with the control group. Included studies had a high risk of bias. Few adverse effects were reported in the included studies, and no serious adverse responses occurred. Adverse effects did not result in any dropouts. Conclusions: All studies indicated that tian jiu therapy has a positive effect on adults with asthma and that it is relatively safe because of its noninvasive nature. However, the limitations of the research design of the existing studies resulted in high risk of bias. More randomized controlled trials of better methodologic quality are needed to further confirm efficacy and safety of this therapy.</description><subject>Acupuncture Points</subject><subject>Acupuncture Therapy</subject><subject>Adult</subject><subject>Asthma - blood</subject><subject>Asthma - drug therapy</subject><subject>Asthma - therapy</subject><subject>Drugs, Chinese Herbal - pharmacology</subject><subject>Drugs, Chinese Herbal - therapeutic use</subject><subject>Eosinophils - metabolism</subject><subject>Humans</subject><subject>Immunoglobulin E - blood</subject><subject>Odds Ratio</subject><subject>Phytotherapy</subject><subject>Review</subject><subject>Review Articles</subject><issn>1075-5535</issn><issn>1557-7708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkbtrHDEQxkWIiR0nZdqgMs2e9VxJLgyLyRMHp7jUYlarzSns4yxpDfffW8s5xq5SzTDz45uP-RD6QMmGEm0uwI0bRqjYEELMK3RGpVSVUkS_Lj1RspKSy1P0NqW_hRDCsDfolEkljSH1GbrdBpjwj7Dg7c5H2B9wP0ecdx5vo4c8-injucdNyrsRcJhw0y1Dxr8gh7JKl7jBP32GqplgOKSQ3qGTHobk3z_Wc_T7y-ft9bfq5vbr9-vmpnKC01wZ0_cdV5qbThilpTSdq0XrqJMtY6JuFWde1LLXSjvFQTOoNafaUQnc1Iafo6uj7n5pR9-5YibCYPcxjBAPdoZgX26msLN_5nsrBOGMySLw6VEgzneLT9mOITk_DDD5eUmW1kowUsAVrY6oi3NK0fdPZyixawi2hGDXEOwaQuE_Pvf2RP_7egH4EVjHME1D8K2P-T-yDxGDkqg</recordid><startdate>20150401</startdate><enddate>20150401</enddate><creator>Chan, Clara W.C.</creator><creator>Lee, Sau Chun</creator><creator>Lo, Kwai Ching</creator><creator>Wong, Hei Kiu</creator><creator>Li, Lei</creator><general>Mary Ann Liebert, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150401</creationdate><title>Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis</title><author>Chan, Clara W.C. ; Lee, Sau Chun ; Lo, Kwai Ching ; Wong, Hei Kiu ; Li, Lei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-99ffd37839d4978559dc64bc1c5b2246b732e465f878c73a82a68318c15a39693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Acupuncture Points</topic><topic>Acupuncture Therapy</topic><topic>Adult</topic><topic>Asthma - blood</topic><topic>Asthma - drug therapy</topic><topic>Asthma - therapy</topic><topic>Drugs, Chinese Herbal - pharmacology</topic><topic>Drugs, Chinese Herbal - therapeutic use</topic><topic>Eosinophils - metabolism</topic><topic>Humans</topic><topic>Immunoglobulin E - blood</topic><topic>Odds Ratio</topic><topic>Phytotherapy</topic><topic>Review</topic><topic>Review Articles</topic><toplevel>online_resources</toplevel><creatorcontrib>Chan, Clara W.C.</creatorcontrib><creatorcontrib>Lee, Sau Chun</creatorcontrib><creatorcontrib>Lo, Kwai Ching</creatorcontrib><creatorcontrib>Wong, Hei Kiu</creatorcontrib><creatorcontrib>Li, Lei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>The journal of alternative and complementary medicine (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chan, Clara W.C.</au><au>Lee, Sau Chun</au><au>Lo, Kwai Ching</au><au>Wong, Hei Kiu</au><au>Li, Lei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis</atitle><jtitle>The journal of alternative and complementary medicine (New York, N.Y.)</jtitle><addtitle>J Altern Complement Med</addtitle><date>2015-04-01</date><risdate>2015</risdate><volume>21</volume><issue>4</issue><spage>2</spage><epage>207</epage><pages>2-207</pages><issn>1075-5535</issn><eissn>1557-7708</eissn><abstract>Objectives: To review and evaluate the efficacy and safety of tian jiu therapy on san fu tian for adults with asthma. Methods: A literature search through August 31, 2013, was done to identify comparative studies evaluating effective rate, pulmonary function, immune response, recurrence rate, quality of life, and adverse events. The Cochrane Library, PubMed, EMBASE, and Chinese National Knowledge Infrastructure were searched; only randomized controlled trials with treatment groups using tian jiu therapy were included. Cochrane Collaboration's risk of bias tool and Review Manager software, version 5.2, were used for the data synthesis. Results: Six studies involving 657 patients were identified. tian jiu therapy was more effective than the control intervention (odds ratio [OR], 3.51; 95% confidence interval [CI], 2.05–6.00; p &lt;0.00001; I 2 =18%). The treatment group had a bigger decrease in IgE level (standard mean difference [SMD], −1.40; 95% CI, −2.18 to −0.63; p =0.0004; I 2 =85%) and Eosinophil (Eos) level (SMD, −4.26; 95% CI, −6.28 to −2.23; p &lt;0.00001; I 2 =91%) compared with the control group. Included studies had a high risk of bias. Few adverse effects were reported in the included studies, and no serious adverse responses occurred. Adverse effects did not result in any dropouts. Conclusions: All studies indicated that tian jiu therapy has a positive effect on adults with asthma and that it is relatively safe because of its noninvasive nature. However, the limitations of the research design of the existing studies resulted in high risk of bias. More randomized controlled trials of better methodologic quality are needed to further confirm efficacy and safety of this therapy.</abstract><cop>United States</cop><pub>Mary Ann Liebert, Inc</pub><pmid>25759906</pmid><doi>10.1089/acm.2014.0009</doi><tpages>206</tpages><oa>free_for_read</oa></addata></record>
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subjects Acupuncture Points
Acupuncture Therapy
Adult
Asthma - blood
Asthma - drug therapy
Asthma - therapy
Drugs, Chinese Herbal - pharmacology
Drugs, Chinese Herbal - therapeutic use
Eosinophils - metabolism
Humans
Immunoglobulin E - blood
Odds Ratio
Phytotherapy
Review
Review Articles
title Tian Jiu Therapy for the Treatment of Asthma in Adult Patients: A Meta-Analysis
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