T‐cell immunoglobulin and mucin domain 4 (TIM‐4) signaling in innate immune‐mediated liver ischemia‐reperfusion injury

Hepatic ischemia‐reperfusion injury (IRI), an innate immunity‐driven inflammation response, occurs in multiple clinical settings including liver resection, transplantation, trauma, and shock. T‐cell immunoglobulin and mucin (TIM)‐4, the only TIM protein not expressed on T cells, is found on macropha...

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