Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii)

Ambient temperature reduction (ATR) can extend the lifespan of organisms, but the underlying mechanism is poorly understood. In this study, cellular degradation activity was evaluated in the muscle of an annual fish ( Nothobranchius rachovii ) reared under high (30 °C), moderate (25 °C), and low (20...

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Veröffentlicht in:	AGE 2015-04, Vol.37 (2), p.33-33, Article 33
Hauptverfasser:	Lu, Cheng-Yen, Hsu, Chin-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Aging - physiology Animals Autophagy Autophagy - physiology Biomarkers Biomedical and Life Sciences Cell Biology Cyprinodontiformes - physiology Fish Geriatrics/Gerontology Heat HSP70 Heat-Shock Proteins - metabolism Laboratories Life Sciences Lysosomes - physiology Microtubule-Associated Proteins - physiology Molecular Medicine Phosphatase Polyubiquitin - metabolism Proteasome Endopeptidase Complex - metabolism Proteins Temperature TOR Serine-Threonine Kinases - metabolism
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