Platinum‐Induced Neurotoxicity and Preventive Strategies: Past, Present, and Future

Neurotoxicity is a burdensome side effect of platinum‐based chemotherapy that prevents administration of the full efficacious dosage and often leads to treatment withdrawal. Peripheral sensory neurotoxicity varies from paresthesia in fingers to ataxic gait, which might be transient or irreversible....

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Veröffentlicht in:	The oncologist (Dayton, Ohio) Ohio), 2015-04, Vol.20 (4), p.411-432
Hauptverfasser:	Avan, Abolfazl, Postma, Tjeerd J., Ceresa, Cecilia, Avan, Amir, Cavaletti, Guido, Giovannetti, Elisa, Peters, Godefridus J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Humans Neuro-Oncology Neuroprotective Agents - pharmacology Neurotoxicity Neurotoxicity Syndromes - diagnosis Neurotoxicity Syndromes - etiology Pathogenesis Pharmacogenetics Platinum Platinum Compounds - adverse effects Platinum Compounds - therapeutic use Polymorphism Polymorphism, Genetic Prevention
Online-Zugang:	Volltext
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