Cross-species antibody microarray interrogation identifies a 3-protein panel of plasma biomarkers for early diagnosis of pancreas cancer

Pancreatic ductal adenocarcinoma (PDA) is the fourth leading cause of cancer-related death in the United States, and its incidence is on the rise. Advanced disease is nearly uniformly lethal, emphasizing the need to identify PDA at its earliest stages. To discover early biomarkers of PDA, we evaluat...

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Veröffentlicht in:	Clinical cancer research 2015-04, Vol.21 (7), p.1764-1771
Hauptverfasser:	Mirus, Justin E, Zhang, Yuzheng, Li, Christopher I, Lokshin, Anna E, Prentice, Ross L, Hingorani, Sunil R, Lampe, Paul D
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Animals Area Under Curve Biomarkers, Tumor - blood Carcinoma, Pancreatic Ductal - blood Carcinoma, Pancreatic Ductal - diagnosis Early Detection of Cancer - methods Female Humans Immunohistochemistry Male Mice Mice, Inbred C57BL Microarray Analysis Middle Aged Pancreatic Neoplasms - blood Pancreatic Neoplasms - diagnosis ROC Curve Sensitivity and Specificity
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