Increased risk of venous thromboembolism is associated with genetic variation in heme oxygenase-1 in Blacks

Abstract Background Venous thromboembolism (VTE) affects as many as 1 in 1000 individuals in the United States. Although Blacks are disproportionately affected by VTE, few genetic risk factors have been identified in this population. The inducible heme oxygenase-1 ( HMOX1 ) gene encodes a key cytopr...

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Veröffentlicht in:	Thrombosis research 2012-12, Vol.130 (6), p.942-947
Hauptverfasser:	Bean, Christopher J, Boulet, Sheree L, Ellingsen, Dorothy, Trau, Heidi, Ghaji, Nafisa, Hooper, W. Craig, Austin, Harland
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans - genetics Alleles Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Case-Control Studies Coronary heart disease Deep vein thrombosis Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous European Continental Ancestry Group - genetics Female Gene Frequency Genetic association Genetic Predisposition to Disease Genetic Variation Heart Hematology, Oncology and Palliative Medicine Heme oxygenase-1 Heme Oxygenase-1 - genetics Humans Logistic Models Male Medical sciences Microsatellite Repeats Middle Aged Oxidative stress Risk Factors Venous Thromboembolism - blood Venous Thromboembolism - enzymology Venous Thromboembolism - ethnology Venous Thromboembolism - genetics
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