The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding

Tspan8 and CD151 are metastasis-promoting tetraspanins and a knockdown (kd) of Tspan8 or CD151 and most pronounced of both tetraspanins affects the metastatic potential of the rat pancreatic adenocarcinoma line ASML. Approaching to elaborate the underlying mechanism, we compared ASMLwt, -CD151kd and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncotarget 2015-02, Vol.6 (4), p.2366-2384
Hauptverfasser:	Yue, Shijing, Mu, Wei, Erb, Ulrike, Zöller, Margot
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Animals Apoptosis - genetics Blotting, Western Cell Adhesion - genetics Cell Adhesion Molecules - metabolism Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Cytokines - metabolism Exosomes - genetics Exosomes - metabolism Extracellular Matrix - metabolism Gene Knockdown Techniques Lymphatic Metastasis Matrix Metalloproteinases - metabolism Microscopy, Confocal Neoplasm Invasiveness Neoplastic Stem Cells - metabolism Pancreatic Neoplasms Pancreatic Neoplasms - genetics Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Rats Research Paper Tetraspanin 24 - genetics Tetraspanin 24 - metabolism Tetraspanins - genetics Tetraspanins - metabolism Vascular Endothelial Growth Factor Receptor-3 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!