Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget

Tylophorine compounds have been the focus of drug development for decades. Tylophorine derivatives exhibit anti-cancer activities but their cellular targets remain unknown. We used a biotinylated tylophorine derivative to probe for the interacting cellular target(s) of tylophorine. Tylophorine direc...

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Veröffentlicht in:Oncotarget 2015-02, Vol.6 (4), p.2148-2163
Hauptverfasser: Qiu, Ya-Qi, Yang, Cheng-Wei, Lee, Yue-Zhi, Yang, Ruey-Bing, Lee, Chih-Hao, Hsu, Hsing-Yu, Chang, Chien-Chung, Lee, Shiow-Ju
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Sprache:eng
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