Ouabain-Induced Cytoplasmic Vesicles and Their Role in Cell Volume Maintenance

Cellular swelling is controlled by an active mechanism of cell volume regulation driven by a Na+/K+-dependent ATPase and by aquaporins which translocate water along the osmotic gradient. Na+/K+-pump may be blocked by ouabain, a digitalic derivative, by inhibition of ATP, or by drastic ion alteration...

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Veröffentlicht in:	BioMed research international 2015-01, Vol.2015 (2015), p.1-13
Hauptverfasser:	Rossum, G. D. van, Russo, A., Morgante, E., Russo, M. A., Tafani, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aquaporins Cell interaction Cell Size Cytoplasm Cytoplasmic Vesicles - metabolism Gangrene Gene expression Health aspects Humans Hypoxia Ion Transport - physiology Metabolism Metabolites Morphology Observations Ouabain Ouabain - metabolism Pathology Plasma Review Rodents Sodium-Potassium-Exchanging ATPase - metabolism Water-Electrolyte Balance - physiology
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