Modulation of MicroRNAs by Phytochemicals in Cancer: Underlying Mechanisms and Translational Significance

MicroRNAs (miRNAs) are small, endogenous noncoding RNAs that regulate a variety of biological processes such as differentiation, development, and survival. Recent studies suggest that miRNAs are dysregulated in cancer and play critical roles in cancer initiation, progression, and chemoresistance. Th...

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Veröffentlicht in:	BioMed research international 2015-01, Vol.2015 (2015), p.1-9
Hauptverfasser:	Singh, Seema, Averett, Courey, Arora, Sumit, Srivastava, Sanjeev K., Singh, Ajay
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biochemical Phenomena - drug effects Biochemical Phenomena - genetics Cancer Cancer therapies Carcinogenesis - drug effects Carcinogenesis - genetics Cell adhesion & migration Drugs Epigenetics Gene expression Genetic aspects Genetic translation Health aspects Humans Leukemia Lung cancer MicroRNA MicroRNAs MicroRNAs - genetics Neoplasms - drug therapy Neoplasms - genetics Neoplasms - pathology Observations Pancreatic cancer Phytochemicals Phytochemicals - pharmacology Phytochemicals - therapeutic use Prostate cancer Review RNA polymerase Studies
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