miR-205 acts as a tumour radiosensitizer by targeting ZEB1 and Ubc13

Tumour cells associated with therapy resistance (radioresistance and drug resistance) are likely to give rise to local recurrence and distant metastatic relapse. Recent studies revealed microRNA (miRNA)-mediated regulation of metastasis and epithelial–mesenchymal transition; however, whether specifi...

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Veröffentlicht in:	Nature communications 2014-12, Vol.5 (1), p.5671-5671, Article 5671
Hauptverfasser:	Zhang, Peijing, Wang, Li, Rodriguez-Aguayo, Cristian, Yuan, Yuan, Debeb, Bisrat G., Chen, Dahu, Sun, Yutong, You, M. James, Liu, Yongqing, Dean, Douglas C., Woodward, Wendy A., Liang, Han, Yang, Xianbin, Lopez-Berestein, Gabriel, Sood, Anil K., Hu, Ye, Ang, K. Kian, Chen, Junjie, Ma, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	631/337/384/331 692/699/67/1059/485 692/699/67/1347 Ataxia Telangiectasia Mutated Proteins - genetics Ataxia Telangiectasia Mutated Proteins - metabolism Cell Line, Tumor DNA Repair - radiation effects Down-Regulation - radiation effects Gene Expression Regulation, Neoplastic - radiation effects Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humanities and Social Sciences Humans MicroRNAs - genetics MicroRNAs - metabolism multidisciplinary Neoplasms - genetics Neoplasms - metabolism Neoplasms - radiotherapy Radiation Tolerance Science Science (multidisciplinary) Transcription Factors - genetics Transcription Factors - metabolism Ubiquitin-Conjugating Enzymes - genetics Ubiquitin-Conjugating Enzymes - metabolism Zinc Finger E-box-Binding Homeobox 1
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