Effects of neutrophil elastase inhibitor in patients undergoing esophagectomy:A systematic review and meta-analysis

AIM: To evaluate the benefit and safety of sivelestat(a neutrophil elastase inhibitor) administration in patients undergoing esophagectomy. METHODS: Online databases including Pub Med, EMBASE, the Cochrane Library, Web of Knowledge, and Chinese databases(Wanfang database, VIP and CNKI) were searched...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2015-03, Vol.21 (12), p.3720-3730
Hauptverfasser:	Wang, Zhi-Qiang, Chen, Long-Qi, Yuan, Yong, Wang, Wen-Ping, Niu, Zhong-Xi, Yang, Yu-Shang, Cai, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - etiology Acute Lung Injury - prevention & control Aged cancer Es elastase Esophagectomy - adverse effects Female Glycine - adverse effects Glycine - analogs & derivatives Glycine - therapeutic use Humans inhibitor Esophageal Leukocyte Elastase - antagonists & inhibitors Leukocyte Elastase - metabolism Male Meta-Analysis Middle Aged Neutrophil Odds Ratio Respiration, Artificial Risk Factors Serine Proteinase Inhibitors - adverse effects Serine Proteinase Inhibitors - therapeutic use Sulfonamides - adverse effects Sulfonamides - therapeutic use Time Factors Treatment Outcome
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