Phosphorylation of Krüppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain-interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity

Krüppel-like factor 3 (KLF3/BKLF), a member of the Krüppel-like factor (KLF) family of transcription factors, is a widely expressed transcriptional repressor with diverse biological roles. Although there is considerable understanding of the molecular mechanisms that allow KLF3 to silence the activit...

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Veröffentlicht in:	The Journal of biological chemistry 2015-03, Vol.290 (13), p.8591-8605
Hauptverfasser:	Dewi, Vitri, Kwok, Alister, Lee, Stella, Lee, Ming Min, Tan, Yee Mun, Nicholas, Hannah R., Isono, Kyo-ichi, Wienert, Beeke, Mak, Ka Sin, Knights, Alexander J., Quinlan, Kate G.R., Cordwell, Stuart J., Funnell, Alister P.W., Pearson, Richard C.M., Crossley, Merlin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Oxidoreductases Amino Acid Sequence Animals C-terminal Binding Protein (CtBP2) Carrier Proteins - physiology Chlorocebus aethiops Co-Repressor Proteins COS Cells DNA - chemistry DNA-Binding Proteins - metabolism Electrophoretic Mobility Shift Assay Gene Expression Gene Regulation Homeodomain-interacting Protein Kinase 2 (HIPK2) Kruppel-like Factor (KLF) Kruppel-like Factor 3 (KLF3/BKLF) Kruppel-Like Transcription Factors - chemistry Kruppel-Like Transcription Factors - metabolism Mice Molecular Sequence Data NIH 3T3 Cells Phosphoproteins - metabolism Phosphorylation Post-translational Modification (PTM) Protein Binding Protein Phosphorylation Protein Processing, Post-Translational Protein-Serine-Threonine Kinases - physiology Transcription Regulation Transcription, Genetic Transcriptional Activation
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