Medullary regulation of visceral sympathetic nerve discharge at peak hyperthermia in aged F344 rats

Abstract Heat stress provides a potent stimulus for the activation of visceral sympathetic nerve discharge (SND) in young but not aged rats. Central mechanisms mediating attenuated SND responses to heating in aged rats have not been investigated. Because the GABAergic system in the rostral ventral l...

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Veröffentlicht in:	Autonomic neuroscience 2014-12, Vol.186, p.32-37
1. Verfasser:	Kenney, M.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Aged F344 rats Aging - physiology Animals Bicuculline Bicuculline - pharmacology Body Temperature - drug effects Body Temperature - physiology Fever - physiopathology GABA-A Receptor Antagonists - pharmacology gamma-Aminobutyric Acid - metabolism Heat stress Kidney - innervation Male Medical Education Medulla Oblongata - physiopathology Physical Stimulation Rats, Inbred F344 Receptors, GABA-A - metabolism Renal sympathetic nerve discharge RVLM Sympathetic Nervous System - physiopathology
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