Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study
Background The prescription of guideline-recommended medication for secondary prevention after acute coronary syndrome has been suboptimal in the past. In the present study, guideline adherence and associated patient, care and hospital characteristics at hospital discharge after acute coronary syndr...
Gespeichert in:
| Veröffentlicht in: | Netherlands heart journal 2015-04, Vol.23 (4), p.214-221 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 221 |
|---|---|
| container_issue | 4 |
| container_start_page | 214 |
| container_title | Netherlands heart journal |
| container_volume | 23 |
| creator | Tra, J. van der Wulp, I. Appelman, Y. de Bruijne, M.C. Wagner, C. |
| description | Background
The prescription of guideline-recommended medication for secondary prevention after acute coronary syndrome has been suboptimal in the past. In the present study, guideline adherence and associated patient, care and hospital characteristics at hospital discharge after acute coronary syndrome were studied.
Methods
Charts of patients with acute coronary syndrome discharged from 13 Dutch hospitals in 2012 were reviewed. Guideline adherence was defined as the prescription of acetylsalicylic acid, P2Y
12
receptor inhibitor, statin, beta-blocker and angiotensin-converting enzyme (ACE) inhibitor at discharge, or a documented contraindication. Associated characteristics were identified by means of generalized linear mixed models for binary outcomes.
Results
In total, 2471 patients were included. Complete guideline adherence was achieved in 69.1 % of the patients, ranging from 42.1 to 87.0 % between hospitals. The ACE inhibitor was most often missing (21.2 %). Patients with non-ST-segment elevation myocardial infarction or unstable angina, patients with a history of coronary artery bypass grafting or elderly women were less likely to be discharged with the guideline-recommended medication.
Conclusions
Guideline adherence for secondary prevention medication following acute coronary syndrome was substantial; however, variation between hospitals and patient groups was found. Efforts to increase guideline adherence can focus on underperforming hospitals and undertreated patient groups. |
| doi_str_mv | 10.1007/s12471-015-0664-y |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4368527</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1674201995</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-2bc47d6ad18b8afd0d0001df114cc7258d99e07b59c244e75c95baea0c8fe19f3</originalsourceid><addsrcrecordid>eNp1UU1v1TAQjBCIlsIP4IIsceESsB07djggVRVfUqVeytly7M2Lq8QOtlMp_4Sfi997pUClnna1Mzu7o6mq1wS_JxiLD4lQJkiNCa9x27J6e1KdEinauqUcPy09b2XNpZQn1YuUbjDmghLxvDqhZchw15xWv87tCBG8AZQD2q3OwuQ8JDSEiPIIaImQTHRLdsGjMKAEJnir47ZHbsEf5jNYZ_Sh1RmNIS0u6wlZl8yo4w6QHjJEpM2aAZkQg98LpM3bGGb4iDSa1yk7U-QioJRXu72sng16SvDqrp5VP758vr74Vl9eff1-cX5ZGyZwrmlfqm21JbKXerDYYoyJHQhhxoji03YdYNHzzlDGQHDT8V6DxkYOQLqhOas-HXWXtS82Di_oSS3RzeVHFbRT_yPejWoXbhVrWsmpKALv7gRi-LlCymoutmGatIewJkVawSgmXccL9e0D6k1Yoy_2FBWSyYZR2hQWObJMDClFGO6fIVjtc1fH3FXJXe1zV1vZefOvi_uNP0EXAj0SUoH8DuLf04-r_gbwOb7Y</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2784834223</pqid></control><display><type>article</type><title>Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study</title><source>Springer Nature OA Free Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Tra, J. ; van der Wulp, I. ; Appelman, Y. ; de Bruijne, M.C. ; Wagner, C.</creator><creatorcontrib>Tra, J. ; van der Wulp, I. ; Appelman, Y. ; de Bruijne, M.C. ; Wagner, C.</creatorcontrib><description>Background
The prescription of guideline-recommended medication for secondary prevention after acute coronary syndrome has been suboptimal in the past. In the present study, guideline adherence and associated patient, care and hospital characteristics at hospital discharge after acute coronary syndrome were studied.
Methods
Charts of patients with acute coronary syndrome discharged from 13 Dutch hospitals in 2012 were reviewed. Guideline adherence was defined as the prescription of acetylsalicylic acid, P2Y
12
receptor inhibitor, statin, beta-blocker and angiotensin-converting enzyme (ACE) inhibitor at discharge, or a documented contraindication. Associated characteristics were identified by means of generalized linear mixed models for binary outcomes.
Results
In total, 2471 patients were included. Complete guideline adherence was achieved in 69.1 % of the patients, ranging from 42.1 to 87.0 % between hospitals. The ACE inhibitor was most often missing (21.2 %). Patients with non-ST-segment elevation myocardial infarction or unstable angina, patients with a history of coronary artery bypass grafting or elderly women were less likely to be discharged with the guideline-recommended medication.
Conclusions
Guideline adherence for secondary prevention medication following acute coronary syndrome was substantial; however, variation between hospitals and patient groups was found. Efforts to increase guideline adherence can focus on underperforming hospitals and undertreated patient groups.</description><identifier>ISSN: 1568-5888</identifier><identifier>EISSN: 1876-6250</identifier><identifier>DOI: 10.1007/s12471-015-0664-y</identifier><identifier>PMID: 25884093</identifier><language>eng</language><publisher>Houten: Bohn Stafleu van Loghum</publisher><subject>Acute coronary syndromes ; Angina pectoris ; Angioplasty ; Aspirin ; Beta blockers ; Body mass index ; Cardiology ; Cardiovascular disease ; Contraindications ; Coronary vessels ; Heart attacks ; Heart failure ; Heart surgery ; Medical Education ; Medicine ; Medicine & Public Health ; Missing data ; Original ; Original Article ; Patient compliance ; Patients ; Prevention ; Quality improvement ; Variables</subject><ispartof>Netherlands heart journal, 2015-04, Vol.23 (4), p.214-221</ispartof><rights>The Author(s) 2015</rights><rights>The Author(s) 2015. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-2bc47d6ad18b8afd0d0001df114cc7258d99e07b59c244e75c95baea0c8fe19f3</citedby><cites>FETCH-LOGICAL-c470t-2bc47d6ad18b8afd0d0001df114cc7258d99e07b59c244e75c95baea0c8fe19f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368527/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368527/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,41099,42168,51554,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25884093$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tra, J.</creatorcontrib><creatorcontrib>van der Wulp, I.</creatorcontrib><creatorcontrib>Appelman, Y.</creatorcontrib><creatorcontrib>de Bruijne, M.C.</creatorcontrib><creatorcontrib>Wagner, C.</creatorcontrib><title>Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study</title><title>Netherlands heart journal</title><addtitle>Neth Heart J</addtitle><addtitle>Neth Heart J</addtitle><description>Background
The prescription of guideline-recommended medication for secondary prevention after acute coronary syndrome has been suboptimal in the past. In the present study, guideline adherence and associated patient, care and hospital characteristics at hospital discharge after acute coronary syndrome were studied.
Methods
Charts of patients with acute coronary syndrome discharged from 13 Dutch hospitals in 2012 were reviewed. Guideline adherence was defined as the prescription of acetylsalicylic acid, P2Y
12
receptor inhibitor, statin, beta-blocker and angiotensin-converting enzyme (ACE) inhibitor at discharge, or a documented contraindication. Associated characteristics were identified by means of generalized linear mixed models for binary outcomes.
Results
In total, 2471 patients were included. Complete guideline adherence was achieved in 69.1 % of the patients, ranging from 42.1 to 87.0 % between hospitals. The ACE inhibitor was most often missing (21.2 %). Patients with non-ST-segment elevation myocardial infarction or unstable angina, patients with a history of coronary artery bypass grafting or elderly women were less likely to be discharged with the guideline-recommended medication.
Conclusions
Guideline adherence for secondary prevention medication following acute coronary syndrome was substantial; however, variation between hospitals and patient groups was found. Efforts to increase guideline adherence can focus on underperforming hospitals and undertreated patient groups.</description><subject>Acute coronary syndromes</subject><subject>Angina pectoris</subject><subject>Angioplasty</subject><subject>Aspirin</subject><subject>Beta blockers</subject><subject>Body mass index</subject><subject>Cardiology</subject><subject>Cardiovascular disease</subject><subject>Contraindications</subject><subject>Coronary vessels</subject><subject>Heart attacks</subject><subject>Heart failure</subject><subject>Heart surgery</subject><subject>Medical Education</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Missing data</subject><subject>Original</subject><subject>Original Article</subject><subject>Patient compliance</subject><subject>Patients</subject><subject>Prevention</subject><subject>Quality improvement</subject><subject>Variables</subject><issn>1568-5888</issn><issn>1876-6250</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNp1UU1v1TAQjBCIlsIP4IIsceESsB07djggVRVfUqVeytly7M2Lq8QOtlMp_4Sfi997pUClnna1Mzu7o6mq1wS_JxiLD4lQJkiNCa9x27J6e1KdEinauqUcPy09b2XNpZQn1YuUbjDmghLxvDqhZchw15xWv87tCBG8AZQD2q3OwuQ8JDSEiPIIaImQTHRLdsGjMKAEJnir47ZHbsEf5jNYZ_Sh1RmNIS0u6wlZl8yo4w6QHjJEpM2aAZkQg98LpM3bGGb4iDSa1yk7U-QioJRXu72sng16SvDqrp5VP758vr74Vl9eff1-cX5ZGyZwrmlfqm21JbKXerDYYoyJHQhhxoji03YdYNHzzlDGQHDT8V6DxkYOQLqhOas-HXWXtS82Di_oSS3RzeVHFbRT_yPejWoXbhVrWsmpKALv7gRi-LlCymoutmGatIewJkVawSgmXccL9e0D6k1Yoy_2FBWSyYZR2hQWObJMDClFGO6fIVjtc1fH3FXJXe1zV1vZefOvi_uNP0EXAj0SUoH8DuLf04-r_gbwOb7Y</recordid><startdate>20150401</startdate><enddate>20150401</enddate><creator>Tra, J.</creator><creator>van der Wulp, I.</creator><creator>Appelman, Y.</creator><creator>de Bruijne, M.C.</creator><creator>Wagner, C.</creator><general>Bohn Stafleu van Loghum</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20150401</creationdate><title>Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study</title><author>Tra, J. ; van der Wulp, I. ; Appelman, Y. ; de Bruijne, M.C. ; Wagner, C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-2bc47d6ad18b8afd0d0001df114cc7258d99e07b59c244e75c95baea0c8fe19f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Acute coronary syndromes</topic><topic>Angina pectoris</topic><topic>Angioplasty</topic><topic>Aspirin</topic><topic>Beta blockers</topic><topic>Body mass index</topic><topic>Cardiology</topic><topic>Cardiovascular disease</topic><topic>Contraindications</topic><topic>Coronary vessels</topic><topic>Heart attacks</topic><topic>Heart failure</topic><topic>Heart surgery</topic><topic>Medical Education</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Missing data</topic><topic>Original</topic><topic>Original Article</topic><topic>Patient compliance</topic><topic>Patients</topic><topic>Prevention</topic><topic>Quality improvement</topic><topic>Variables</topic><toplevel>online_resources</toplevel><creatorcontrib>Tra, J.</creatorcontrib><creatorcontrib>van der Wulp, I.</creatorcontrib><creatorcontrib>Appelman, Y.</creatorcontrib><creatorcontrib>de Bruijne, M.C.</creatorcontrib><creatorcontrib>Wagner, C.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Netherlands heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tra, J.</au><au>van der Wulp, I.</au><au>Appelman, Y.</au><au>de Bruijne, M.C.</au><au>Wagner, C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study</atitle><jtitle>Netherlands heart journal</jtitle><stitle>Neth Heart J</stitle><addtitle>Neth Heart J</addtitle><date>2015-04-01</date><risdate>2015</risdate><volume>23</volume><issue>4</issue><spage>214</spage><epage>221</epage><pages>214-221</pages><issn>1568-5888</issn><eissn>1876-6250</eissn><abstract>Background
The prescription of guideline-recommended medication for secondary prevention after acute coronary syndrome has been suboptimal in the past. In the present study, guideline adherence and associated patient, care and hospital characteristics at hospital discharge after acute coronary syndrome were studied.
Methods
Charts of patients with acute coronary syndrome discharged from 13 Dutch hospitals in 2012 were reviewed. Guideline adherence was defined as the prescription of acetylsalicylic acid, P2Y
12
receptor inhibitor, statin, beta-blocker and angiotensin-converting enzyme (ACE) inhibitor at discharge, or a documented contraindication. Associated characteristics were identified by means of generalized linear mixed models for binary outcomes.
Results
In total, 2471 patients were included. Complete guideline adherence was achieved in 69.1 % of the patients, ranging from 42.1 to 87.0 % between hospitals. The ACE inhibitor was most often missing (21.2 %). Patients with non-ST-segment elevation myocardial infarction or unstable angina, patients with a history of coronary artery bypass grafting or elderly women were less likely to be discharged with the guideline-recommended medication.
Conclusions
Guideline adherence for secondary prevention medication following acute coronary syndrome was substantial; however, variation between hospitals and patient groups was found. Efforts to increase guideline adherence can focus on underperforming hospitals and undertreated patient groups.</abstract><cop>Houten</cop><pub>Bohn Stafleu van Loghum</pub><pmid>25884093</pmid><doi>10.1007/s12471-015-0664-y</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1568-5888 |
| ispartof | Netherlands heart journal, 2015-04, Vol.23 (4), p.214-221 |
| issn | 1568-5888 1876-6250 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4368527 |
| source | Springer Nature OA Free Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Acute coronary syndromes Angina pectoris Angioplasty Aspirin Beta blockers Body mass index Cardiology Cardiovascular disease Contraindications Coronary vessels Heart attacks Heart failure Heart surgery Medical Education Medicine Medicine & Public Health Missing data Original Original Article Patient compliance Patients Prevention Quality improvement Variables |
| title | Adherence to guidelines for the prescription of secondary prevention medication at hospital discharge after acute coronary syndrome: a multicentre study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T02%3A21%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adherence%20to%20guidelines%20for%20the%20prescription%20of%20secondary%20prevention%20medication%20at%20hospital%20discharge%20after%20acute%20coronary%20syndrome:%20a%20multicentre%20study&rft.jtitle=Netherlands%20heart%20journal&rft.au=Tra,%20J.&rft.date=2015-04-01&rft.volume=23&rft.issue=4&rft.spage=214&rft.epage=221&rft.pages=214-221&rft.issn=1568-5888&rft.eissn=1876-6250&rft_id=info:doi/10.1007/s12471-015-0664-y&rft_dat=%3Cproquest_pubme%3E1674201995%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2784834223&rft_id=info:pmid/25884093&rfr_iscdi=true |