Personalized dose selection in radiation therapy using statistical models for toxicity and efficacy with dose and biomarkers as covariates

Selection of dose for cancer patients treated with radiation therapy (RT) must balance the increased efficacy with the increased toxicity associated with higher dose. Historically, a single dose has been selected for a population of patients (e.g., all stage III non‐small cell lung cancer). However,...

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Veröffentlicht in:Statistics in medicine 2014-12, Vol.33 (30), p.5330-5339
Hauptverfasser: Schipper, Matthew J., Taylor, Jeremy M. G., TenHaken, Randy, Matuzak, Martha M., Kong, Feng-Ming, Lawrence, Theodore S.
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Sprache:eng
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