Control of Ethanol Sensitivity of the Glycine Receptor α3 Subunit by Transmembrane 2, the Intracellular Splice Cassette and C-Terminal Domain

Previous studies have shown that the effect of ethanol on glycine receptors (GlyRs) containing the α 1 subunit is affected by interaction with heterotrimeric G proteins (G βγ ). GlyRs containing the α 3 subunit are involved in inflammatory pain sensitization and rhythmic breathing and have received...

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Veröffentlicht in:The Journal of pharmacology and experimental therapeutics 2015-04, Vol.353 (1), p.80-90
Hauptverfasser: Sánchez, Andrea, Yévenes, Gonzalo E., San Martin, Loreto, Burgos, Carlos F., Moraga-Cid, Gustavo, Harvey, Robert J., Aguayo, Luis G.
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Sprache:eng
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