Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour

Anticancer therapies are often compromised by nonspecific effects and challenged by tumour environments’ inherent physicochemical and biological characteristics. Often, therapeutic effect can be increased by addressing multiple parameters simultaneously. Here we report on exploiting extravasation du...

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Veröffentlicht in:	Nature communications 2015-03, Vol.6 (1), p.6456-6456, Article 6456
Hauptverfasser:	Tseng, S.-Ja, Liao, Zi-Xian, Kao, Shih-Han, Zeng, Yi-Fang, Huang, Kuo-Yen, Li, Hsin-Jung, Yang, Chung-Lin, Deng, Yu-Fan, Huang, Chi-Feng, Yang, Shuenn-Chen, Yang, Pan-Chyr, Kempson, Ivan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/109 13/2 13/31 14/19 14/35 14/63 631/1647/2300 631/67/1059/99 631/80/82/23 64/60 82/80 96/44 Animals Apoptosis Apoptosis - physiology Cancer therapies Carcinoma, Non-Small-Cell Lung - therapy Cell cycle Cell Line, Tumor Chemotherapy Dimethyl Sulfoxide Endosomes - metabolism Gene Transfer Techniques Glutamates Green Fluorescent Proteins - metabolism Humanities and Social Sciences Humans Hydrogen-Ion Concentration In Situ Nick-End Labeling Indoles Magnetic Resonance Spectroscopy Metastasis Mice Mice, Inbred BALB C multidisciplinary Photochemotherapy - methods Proteins Science Science (multidisciplinary) Tumor Microenvironment - physiology Tumor Suppressor Protein p53 - metabolism
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