Posttraumatic stress disorder and incident heart failure among a community-based sample of US veterans
We investigated the association between posttraumatic stress disorder (PTSD) and incident heart failure in a community-based sample of veterans. We examined Veterans Affairs Pacific Islands Health Care System outpatient medical records for 8248 veterans between 2005 and 2012. We used multivariable C...
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| Veröffentlicht in: | American journal of public health (1971) 2015-04, Vol.105 (4), p.757-763 |
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| creator | Roy, Samit S Foraker, Randi E Girton, Richard A Mansfield, Alyssa J |
| description | We investigated the association between posttraumatic stress disorder (PTSD) and incident heart failure in a community-based sample of veterans.
We examined Veterans Affairs Pacific Islands Health Care System outpatient medical records for 8248 veterans between 2005 and 2012. We used multivariable Cox regression to estimate hazard ratios and 95% confidence intervals for the development of heart failure by PTSD status.
Over a mean follow-up of 7.2 years, veterans with PTSD were at increased risk for developing heart failure (hazard ratio [HR] = 1.47; 95% confidence interval [CI] = 1.13, 1.92) compared with veterans without PTSD after adjustment for age, gender, diabetes, hyperlipidemia, hypertension, body mass index, combat service, and military service period. Additional predictors for heart failure included age (HR = 1.05; 95% CI = 1.03, 1.07), diabetes (HR = 2.54; 95% CI = 2.02, 3.20), hypertension (HR = 1.87; 95% CI = 1.42, 2.46), overweight (HR = 1.72; 95% CI = 1.25, 2.36), obesity (HR = 3.43; 95% CI = 2.50, 4.70), and combat service (HR = 4.99; 95% CI = 1.29, 19.38).
Ours is the first large-scale longitudinal study to report an association between PTSD and incident heart failure in an outpatient sample of US veterans. Prevention and treatment efforts for heart failure and its associated risk factors should be expanded among US veterans with PTSD. |
| doi_str_mv | 10.2105/AJPH.2014.302342 |
| format | Article |
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We examined Veterans Affairs Pacific Islands Health Care System outpatient medical records for 8248 veterans between 2005 and 2012. We used multivariable Cox regression to estimate hazard ratios and 95% confidence intervals for the development of heart failure by PTSD status.
Over a mean follow-up of 7.2 years, veterans with PTSD were at increased risk for developing heart failure (hazard ratio [HR] = 1.47; 95% confidence interval [CI] = 1.13, 1.92) compared with veterans without PTSD after adjustment for age, gender, diabetes, hyperlipidemia, hypertension, body mass index, combat service, and military service period. Additional predictors for heart failure included age (HR = 1.05; 95% CI = 1.03, 1.07), diabetes (HR = 2.54; 95% CI = 2.02, 3.20), hypertension (HR = 1.87; 95% CI = 1.42, 2.46), overweight (HR = 1.72; 95% CI = 1.25, 2.36), obesity (HR = 3.43; 95% CI = 2.50, 4.70), and combat service (HR = 4.99; 95% CI = 1.29, 19.38).
Ours is the first large-scale longitudinal study to report an association between PTSD and incident heart failure in an outpatient sample of US veterans. Prevention and treatment efforts for heart failure and its associated risk factors should be expanded among US veterans with PTSD.</description><identifier>ISSN: 0090-0036</identifier><identifier>EISSN: 1541-0048</identifier><identifier>DOI: 10.2105/AJPH.2014.302342</identifier><identifier>PMID: 25713943</identifier><identifier>CODEN: AJPHDS</identifier><language>eng</language><publisher>United States: American Public Health Association</publisher><subject>Acute coronary syndromes ; Age Factors ; Aged ; Aged, 80 and over ; Body mass index ; Cardiovascular disease ; Comorbidity ; Confidence intervals ; Continental Population Groups ; Coronary vessels ; Diabetes ; Drug therapy ; Epidemiology ; Female ; Heart attacks ; Heart failure ; Heart Failure - epidemiology ; Humans ; Hyperlipidemia ; Hypertension ; Investigations ; Longitudinal Studies ; Male ; Marital status ; Medical records ; Mental Health ; Mental health care ; Middle Aged ; Military service ; Mortality ; Nervous system ; Other Chronic Disease ; Other Statistics/Evaluation/Research ; Overweight ; Pacific Islands - epidemiology ; Post traumatic stress disorder ; Public health ; Research and Practice ; Risk Factors ; Sex Factors ; Stress Disorders, Post-Traumatic - epidemiology ; Studies ; Time Factors ; United States ; Vein & artery diseases ; Veterans ; Veterans - statistics & numerical data ; World War II</subject><ispartof>American journal of public health (1971), 2015-04, Vol.105 (4), p.757-763</ispartof><rights>Copyright American Public Health Association Apr 2015</rights><rights>American Public Health Association 2015 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c556t-fce9045cf2974e0cc428f2831ca981c9dc4368f776057be054db6992ca73541a3</citedby><cites>FETCH-LOGICAL-c556t-fce9045cf2974e0cc428f2831ca981c9dc4368f776057be054db6992ca73541a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358172/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358172/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27843,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25713943$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Roy, Samit S</creatorcontrib><creatorcontrib>Foraker, Randi E</creatorcontrib><creatorcontrib>Girton, Richard A</creatorcontrib><creatorcontrib>Mansfield, Alyssa J</creatorcontrib><title>Posttraumatic stress disorder and incident heart failure among a community-based sample of US veterans</title><title>American journal of public health (1971)</title><addtitle>Am J Public Health</addtitle><description>We investigated the association between posttraumatic stress disorder (PTSD) and incident heart failure in a community-based sample of veterans.
We examined Veterans Affairs Pacific Islands Health Care System outpatient medical records for 8248 veterans between 2005 and 2012. We used multivariable Cox regression to estimate hazard ratios and 95% confidence intervals for the development of heart failure by PTSD status.
Over a mean follow-up of 7.2 years, veterans with PTSD were at increased risk for developing heart failure (hazard ratio [HR] = 1.47; 95% confidence interval [CI] = 1.13, 1.92) compared with veterans without PTSD after adjustment for age, gender, diabetes, hyperlipidemia, hypertension, body mass index, combat service, and military service period. Additional predictors for heart failure included age (HR = 1.05; 95% CI = 1.03, 1.07), diabetes (HR = 2.54; 95% CI = 2.02, 3.20), hypertension (HR = 1.87; 95% CI = 1.42, 2.46), overweight (HR = 1.72; 95% CI = 1.25, 2.36), obesity (HR = 3.43; 95% CI = 2.50, 4.70), and combat service (HR = 4.99; 95% CI = 1.29, 19.38).
Ours is the first large-scale longitudinal study to report an association between PTSD and incident heart failure in an outpatient sample of US veterans. Prevention and treatment efforts for heart failure and its associated risk factors should be expanded among US veterans with PTSD.</description><subject>Acute coronary syndromes</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body mass index</subject><subject>Cardiovascular disease</subject><subject>Comorbidity</subject><subject>Confidence intervals</subject><subject>Continental Population Groups</subject><subject>Coronary vessels</subject><subject>Diabetes</subject><subject>Drug therapy</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Heart attacks</subject><subject>Heart failure</subject><subject>Heart Failure - epidemiology</subject><subject>Humans</subject><subject>Hyperlipidemia</subject><subject>Hypertension</subject><subject>Investigations</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Marital status</subject><subject>Medical records</subject><subject>Mental Health</subject><subject>Mental health care</subject><subject>Middle Aged</subject><subject>Military service</subject><subject>Mortality</subject><subject>Nervous system</subject><subject>Other Chronic Disease</subject><subject>Other Statistics/Evaluation/Research</subject><subject>Overweight</subject><subject>Pacific Islands - epidemiology</subject><subject>Post traumatic stress disorder</subject><subject>Public health</subject><subject>Research and Practice</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Stress Disorders, Post-Traumatic - epidemiology</subject><subject>Studies</subject><subject>Time Factors</subject><subject>United States</subject><subject>Vein & artery diseases</subject><subject>Veterans</subject><subject>Veterans - statistics & numerical data</subject><subject>World War 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stress disorder and incident heart failure among a community-based sample of US veterans</title><author>Roy, Samit S ; Foraker, Randi E ; Girton, Richard A ; Mansfield, Alyssa J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c556t-fce9045cf2974e0cc428f2831ca981c9dc4368f776057be054db6992ca73541a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Acute coronary syndromes</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Body mass index</topic><topic>Cardiovascular disease</topic><topic>Comorbidity</topic><topic>Confidence intervals</topic><topic>Continental Population Groups</topic><topic>Coronary vessels</topic><topic>Diabetes</topic><topic>Drug therapy</topic><topic>Epidemiology</topic><topic>Female</topic><topic>Heart attacks</topic><topic>Heart failure</topic><topic>Heart Failure - 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Health</addtitle><date>2015-04</date><risdate>2015</risdate><volume>105</volume><issue>4</issue><spage>757</spage><epage>763</epage><pages>757-763</pages><issn>0090-0036</issn><eissn>1541-0048</eissn><coden>AJPHDS</coden><abstract>We investigated the association between posttraumatic stress disorder (PTSD) and incident heart failure in a community-based sample of veterans.
We examined Veterans Affairs Pacific Islands Health Care System outpatient medical records for 8248 veterans between 2005 and 2012. We used multivariable Cox regression to estimate hazard ratios and 95% confidence intervals for the development of heart failure by PTSD status.
Over a mean follow-up of 7.2 years, veterans with PTSD were at increased risk for developing heart failure (hazard ratio [HR] = 1.47; 95% confidence interval [CI] = 1.13, 1.92) compared with veterans without PTSD after adjustment for age, gender, diabetes, hyperlipidemia, hypertension, body mass index, combat service, and military service period. Additional predictors for heart failure included age (HR = 1.05; 95% CI = 1.03, 1.07), diabetes (HR = 2.54; 95% CI = 2.02, 3.20), hypertension (HR = 1.87; 95% CI = 1.42, 2.46), overweight (HR = 1.72; 95% CI = 1.25, 2.36), obesity (HR = 3.43; 95% CI = 2.50, 4.70), and combat service (HR = 4.99; 95% CI = 1.29, 19.38).
Ours is the first large-scale longitudinal study to report an association between PTSD and incident heart failure in an outpatient sample of US veterans. Prevention and treatment efforts for heart failure and its associated risk factors should be expanded among US veterans with PTSD.</abstract><cop>United States</cop><pub>American Public Health Association</pub><pmid>25713943</pmid><doi>10.2105/AJPH.2014.302342</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acute coronary syndromes Age Factors Aged Aged, 80 and over Body mass index Cardiovascular disease Comorbidity Confidence intervals Continental Population Groups Coronary vessels Diabetes Drug therapy Epidemiology Female Heart attacks Heart failure Heart Failure - epidemiology Humans Hyperlipidemia Hypertension Investigations Longitudinal Studies Male Marital status Medical records Mental Health Mental health care Middle Aged Military service Mortality Nervous system Other Chronic Disease Other Statistics/Evaluation/Research Overweight Pacific Islands - epidemiology Post traumatic stress disorder Public health Research and Practice Risk Factors Sex Factors Stress Disorders, Post-Traumatic - epidemiology Studies Time Factors United States Vein & artery diseases Veterans Veterans - statistics & numerical data World War II |
| title | Posttraumatic stress disorder and incident heart failure among a community-based sample of US veterans |
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