Lipoprotein lipase variants interact with polyunsaturated fatty acids for obesity traits in women: Replication in two populations

Abstract Background and aims Lipoprotein lipase ( LPL ) is a candidate gene for obesity based on its role in triglyceride hydrolysis and the partitioning of fatty acids towards storage or oxidation. Whether dietary fatty acids modify LPL associated obesity risk is unknown. Methods and results We exa...

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Veröffentlicht in:	Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2014-12, Vol.24 (12), p.1323-1329
Hauptverfasser:	Ma, Y, Tucker, K.L, Smith, C.E, Lee, Y.C, Huang, T, Richardson, K, Parnell, L.D, Lai, C.Q, Young, K.L, Justice, A.E, Shao, Y, North, K.E, Ordovás, J.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Atherosclerosis - epidemiology Body Mass Index Boston Cardiovascular Diet European Continental Ancestry Group Fatty Acids, Unsaturated - blood Feeding Behavior Female Gene-diet interaction Hispanic Americans Humans Indians, North American Linkage Disequilibrium Lipoprotein lipase Lipoprotein Lipase - genetics Lipoprotein Lipase - metabolism Male Middle Aged Obesity Obesity - enzymology Obesity - epidemiology Obesity - genetics Polymorphism, Single Nucleotide - genetics Polyunsaturated fatty acids
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