Liquid chromatographic method for irinotecan estimation: Screening of p-gp modulators

The present work is aimed to develop a simple, sensitive, robust and reliable HPLC method for the estimation of irinotecan in the physiological media in order to assess the permeability profile of irinotecan, using the everted gut sac, in the presence of various P-gp modulators. Separation was achie...

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Veröffentlicht in:	Indian journal of pharmaceutical sciences 2015-01, Vol.77 (1), p.14-23
Hauptverfasser:	Tariq, M, Negi, L, Talegaonkar, Sushama, Ahmad, F, Iqbal, Zeenat, Khan, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromatography Drug delivery systems Genetic aspects High performance liquid chromatography Irinotecan Measurement Permeability Pharmaceuticals Research Paper Studies
Online-Zugang:	Volltext
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