A QM-MD simulation approach to the analysis of FRET processes in (bio)molecular systems. A case study: complexes of E. coli purine nucleoside phosphorylase and its mutants with formycin A

Predicting FRET pathways in proteins using computer simulation techniques is very important for reliable interpretation of experimental data. A novel and relatively simple methodology has been developed and applied to purine nucleoside phosphorylase (PNP) complexed with a fluorescent ligand — formyc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of molecular modeling 2015-04, Vol.21 (4), p.75, Article 75
Hauptverfasser:	Sobieraj, M., Krzyśko, K. A., Jarmuła, A., Kalinowski, M. W., Lesyng, B., Prokopowicz, M., Cieśla, J., Gojdź, A., Kierdaszuk, B.
Format:	Artikel
Sprache:	eng
Schlagworte:	6th conference on Modeling & Design of Molecular Materials in Kudowa Zdrój (MDMM 2014) Binding Sites Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Computer Appl. in Life Sciences Computer Applications in Chemistry Computer Simulation Escherichia coli - enzymology Escherichia coli - genetics Fluorescence Resonance Energy Transfer Formycins - chemistry Formycins - pharmacology Ligands Molecular Medicine Mutation Original Paper Protein Conformation Purine-Nucleoside Phosphorylase - chemistry Purine-Nucleoside Phosphorylase - genetics Purine-Nucleoside Phosphorylase - metabolism Spectrometry, Fluorescence Substrate Specificity Theoretical and Computational Chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!