Milk Proteins, Peptides, and Oligosaccharides: Effects against the 21st Century Disorders
Milk is the most complete food for mammals, as it supplies all the energy and nutrients needed for the proper growth and development of the neonate. Milk is a source of many bioactive components, which not only help meeting the nutritional requirements of the consumers, but also play a relevant role...
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| Veröffentlicht in: | BioMed research international 2015-01, Vol.2015 (2015), p.1-16 |
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| creator | Barile, Daniela Weinborn, Valerie Fernández-Tomé, Samuel Hernández-Ledesma, Blanca Hsieh, Chia-Chien Maria Leite Nobrega de Moura Bell, Juliana |
| description | Milk is the most complete food for mammals, as it supplies all the energy and nutrients needed for the proper growth and development of the neonate. Milk is a source of many bioactive components, which not only help meeting the nutritional requirements of the consumers, but also play a relevant role in preventing various disorders. Milk-derived proteins and peptides have the potential to act as coadjuvants in conventional therapies, addressing cardiovascular diseases, metabolic disorders, intestinal health, and chemopreventive properties. In addition to being a source of proteins and peptides, milk contains complex oligosaccharides that possess important functions related to the newborn’s development and health. Some of the health benefits attributed to milk oligosaccharides include prebiotic probifidogenic effects, antiadherence of pathogenic bacteria, and immunomodulation. This review focuses on recent findings demonstrating the biological activities of milk peptides, proteins, and oligosaccharides towards the prevention of diseases of the 21st century. Processing challenges hindering large-scale production and commercialization of those bioactive compounds have been also addressed. |
| doi_str_mv | 10.1155/2015/146840 |
| format | Article |
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Milk is a source of many bioactive components, which not only help meeting the nutritional requirements of the consumers, but also play a relevant role in preventing various disorders. Milk-derived proteins and peptides have the potential to act as coadjuvants in conventional therapies, addressing cardiovascular diseases, metabolic disorders, intestinal health, and chemopreventive properties. In addition to being a source of proteins and peptides, milk contains complex oligosaccharides that possess important functions related to the newborn’s development and health. Some of the health benefits attributed to milk oligosaccharides include prebiotic probifidogenic effects, antiadherence of pathogenic bacteria, and immunomodulation. This review focuses on recent findings demonstrating the biological activities of milk peptides, proteins, and oligosaccharides towards the prevention of diseases of the 21st century. Processing challenges hindering large-scale production and commercialization of those bioactive compounds have been also addressed.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2015/146840</identifier><identifier>PMID: 25789308</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Animals ; Breastfeeding & lactation ; Chronic illnesses ; Disease prevention ; Health ; Health aspects ; Health Promotion - methods ; Humans ; Milk ; Milk - metabolism ; Milk proteins ; Milk Proteins - metabolism ; Oligosaccharides ; Oligosaccharides - metabolism ; Peptides - metabolism ; Review</subject><ispartof>BioMed research international, 2015-01, Vol.2015 (2015), p.1-16</ispartof><rights>Copyright © 2015 Chia-Chien Hsieh et al.</rights><rights>COPYRIGHT 2015 John Wiley & Sons, Inc.</rights><rights>Copyright © 2015 Chia-Chien Hsieh et al. Chia-Chien Hsieh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2015 Chia-Chien Hsieh et al. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c594t-fe6569d9b7cacc779bccb76be8dfa9849ef5fba3408c0f701b9144aaacf0777e3</citedby><cites>FETCH-LOGICAL-c594t-fe6569d9b7cacc779bccb76be8dfa9849ef5fba3408c0f701b9144aaacf0777e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350585/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350585/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25789308$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Ren, Jinsong</contributor><creatorcontrib>Barile, Daniela</creatorcontrib><creatorcontrib>Weinborn, Valerie</creatorcontrib><creatorcontrib>Fernández-Tomé, Samuel</creatorcontrib><creatorcontrib>Hernández-Ledesma, Blanca</creatorcontrib><creatorcontrib>Hsieh, Chia-Chien</creatorcontrib><creatorcontrib>Maria Leite Nobrega de Moura Bell, Juliana</creatorcontrib><title>Milk Proteins, Peptides, and Oligosaccharides: Effects against the 21st Century Disorders</title><title>BioMed research international</title><addtitle>Biomed Res Int</addtitle><description>Milk is the most complete food for mammals, as it supplies all the energy and nutrients needed for the proper growth and development of the neonate. 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| subjects | Animals Breastfeeding & lactation Chronic illnesses Disease prevention Health Health aspects Health Promotion - methods Humans Milk Milk - metabolism Milk proteins Milk Proteins - metabolism Oligosaccharides Oligosaccharides - metabolism Peptides - metabolism Review |
| title | Milk Proteins, Peptides, and Oligosaccharides: Effects against the 21st Century Disorders |
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