Arterial grafts exhibiting unprecedented cellular infiltration and remodeling in vivo: The role of cells in the vascular wall

Abstract Objective To engineer and implant vascular grafts in the arterial circulation of a pre-clinical animal model and assess the role of donor medial cells in graft remodeling and function. Approach and results Vascular grafts were engineered using Small Intestinal Submucosa (SIS)-fibrin hybrid...

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Veröffentlicht in:	Biomaterials 2015-05, Vol.50, p.115-126
Hauptverfasser:	Row, Sindhu, Peng, Haofan, Schlaich, Evan M, Koenigsknecht, Carmon, Andreadis, Stelios T, Swartz, Daniel D
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Angiography Animals Apoptosis Arteries - cytology Arteries - diagnostic imaging Biomedical materials Blood Vessel Prosthesis Cell Proliferation Cell-free medial layer Cellular Circulation Dentistry Female Grafts Hair follicle stem cells Immunohistochemistry Infiltration Macrophages - cytology Male Ovine animal model Prosthesis Implantation Regional Blood Flow Remodeling Sheep Small intestinal submucosa Surgical implants Tissue engineered artery Tissue Engineering Ultrasonography Vascular graft Vascular Patency Vascular Remodeling
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