Eimeria bovis-triggered neutrophil extracellular trap formation is CD11b-, ERK 1/2-, p38 MAP kinase- and SOCE-dependent

Eimeria bovis is an important coccidian parasite that causes high economic losses in the cattle industry. We recently showed that polymorphonuclear neutrophils (PMN) react upon E. bovis sporozoite exposure by neutrophil extracellular trap (NET) formation. We focused here on the molecular mechanisms...

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Veröffentlicht in:	Veterinary research (Paris) 2015-03, Vol.46 (1), p.23-23
Hauptverfasser:	Muñoz-Caro, Tamara, Mena Huertas, Sandra Jaqueline, Conejeros, Ivan, Alarcón, Pablo, Hidalgo, María A, Burgos, Rafael A, Hermosilla, Carlos, Taubert, Anja
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals calcium Cattle Cattle Diseases - immunology Cattle Diseases - parasitology Coccidiosis - immunology Coccidiosis - parasitology Coccidiosis - veterinary Eimeria - immunology Eimeria - ultrastructure Eimeria bovis elastase Extracellular Traps - immunology gelatinase B granules host specificity Immunity, Innate industry Life Sciences Microscopy, Electron, Scanning - veterinary Microscopy, Fluorescence - veterinary mitogen-activated protein kinase myeloperoxidase NADP (coenzyme) neutrophils Neutrophils - immunology parasites phosphorylation signal transduction Sporozoites - immunology Sporozoites - ultrastructure
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