Inverse Size Scaling of the Nucleolus by a Concentration-Dependent Phase Transition

Just as organ size typically increases with body size, the size of intracellular structures changes as cells grow and divide. Indeed, many organelles, such as the nucleus [1, 2], mitochondria [3], mitotic spindle [4, 5], and centrosome [6], exhibit size scaling, a phenomenon in which organelle size...

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Veröffentlicht in:	Current biology 2015-03, Vol.25 (5), p.641-646
Hauptverfasser:	Weber, Stephanie C., Brangwynne, Clifford P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans - cytology Caenorhabditis elegans - embryology Cell Nucleolus - physiology Cell Nucleolus - ultrastructure Cell Size Feedback, Physiological Fluorescence Image Processing, Computer-Assisted Microscopy, Confocal Models, Biological RNA Interference
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