Supramolecular protein assembly supports immobilization of a cytochrome P450 monooxygenase system as water-insoluble gel

Diverse applications of the versatile bacterial cytochrome P450 enzymes (P450s) are hampered by their requirement for the auxiliary proteins, ferredoxin reductases and ferredoxins, that transfer electrons to P450s. Notably, this limits the use of P450s as immobilized enzymes for industrial purposes....

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Veröffentlicht in:	Scientific reports 2015-03, Vol.5 (1), p.8648-8648, Article 8648
Hauptverfasser:	Tan, Cheau Yuaan, Hirakawa, Hidehiko, Nagamune, Teruyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	631/45/603 631/45/607/1162 631/45/607/1167 631/61/54/1754 82/16 82/80 82/83 Cytochrome Cytochrome P-450 Enzyme System - metabolism Cytochrome P450 Cytochrome P450 monooxygenase Electron transfer Electron Transport Enzymes Enzymes, Immobilized Ferredoxin Gels - chemistry Humanities and Social Sciences Immobilization Immobilized enzymes Kinetics multidisciplinary Multiprotein Complexes - chemistry Multiprotein Complexes - metabolism NAD NADH NADH, NADPH Oxidoreductases - metabolism Oxidation Oxidation-Reduction Oxygen Consumption Phosphite dehydrogenase Proliferating cell nuclear antigen Protein Multimerization Proteins Science Solubility
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