Micro-scale and meso-scale architectural cues cooperate and compete to direct aligned tissue formation

Abstract Tissue and biomaterial microenvironments provide architectural cues that direct important cell behaviors including cell shape, alignment, migration, and resulting tissue formation. These architectural features may be presented to cells across multiple length scales, from nanometers to milli...

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Veröffentlicht in:	Biomaterials 2014-12, Vol.35 (38), p.10015-10024
Hauptverfasser:	Gilchrist, Christopher L, Ruch, David S, Little, Dianne, Guilak, Farshid
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Advanced Basic Science Alignment Architecture Batch Cell Culture Techniques - methods Biomedical materials Cell Adhesion - physiology Cell Communication - physiology Cell Movement - physiology Cell Polarity - physiology Cell Proliferation - physiology Cells, Cultured Cellular Microenvironment - physiology Collagens Cues Dentistry Formations Guided Tissue Regeneration - methods Humans Ligament Mesenchymal stem cell Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - physiology Micropatterning Nanostructures - chemistry Nanostructures - ultrastructure Nanotopography Organizations Particle Size Surface Properties Surgical implants Tendon Tissue Engineering - methods Tissue Scaffolds
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