Recognition of DNA by ω protein from the broad‐host range Streptococcus pyogenes plasmid pSM19035: analysis of binding to operator DNA with one to four heptad repeats

pSM19035‐encoded ω protein forms a dimer (ω2) that binds to a set of 7‐bp repeats with sequence 5′‐NATCACN‐3′. Upon binding to its cognate sites, ω2 regulates transcription of genes required for copy number control and stable inheritance of plasmids, and promotes accurate plasmid segregation. Protei...

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