Cell-autonomous sex differences in gene expression in chicken bone marrow-derived macrophages

We have identified differences in gene expression in macrophages grown from the bone marrow of male and female chickens in recombinant chicken M-CSF (CSF1). Cells were profiled with or without treatment with bacterial LPS for 24 h. Approximately 600 transcripts were induced by prolonged LPS stimulat...

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Veröffentlicht in:	The Journal of immunology (1950) 2015-03, Vol.194 (5), p.2338-2344
Hauptverfasser:	Garcia-Morales, Carla, Nandi, Sunil, Zhao, Debiao, Sauter, Kristin A, Vervelde, Lonneke, McBride, Derek, Sang, Helen M, Clinton, Mike, Hume, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aromatase Inhibitors - pharmacology Avian Proteins - genetics Avian Proteins - immunology Cells, Cultured Chick Embryo Chickens - genetics Chickens - immunology Dosage Compensation, Genetic Fadrozole - pharmacology Female Gene Expression Gene Expression Profiling Gonads - drug effects Gonads - immunology Innate Immunity and Inflammation Interferon-alpha - genetics Interferon-alpha - immunology Interferon-beta - genetics Interferon-beta - immunology Lipopolysaccharides - pharmacology Macrophage Colony-Stimulating Factor - pharmacology Macrophages - cytology Macrophages - drug effects Macrophages - immunology Male RNA, Messenger - genetics RNA, Messenger - immunology Sex Characteristics Sex Chromosomes - immunology
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