Association of the Apolipoprotein E 2 Allele with Concurrent Occurrence of Endometrial Hyperplasia and Endometrial Carcinoma

Genes encoding proteins with antioxidant properties may influence susceptibility to endometrial hyperplasia (EH) and endometrial carcinoma (ECa). Patients with EH (n = 89), EH concurrent with ECa (n = 76), ECa (n = 186), and healthy controls (n = 1110) were genotyped for five polymorphic variants in...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2015-01, Vol.2015 (2015), p.1-10
Hauptverfasser:	Khorokhorina, Vera A., Mkrtchyan, Liana S., Ryabchenko, Nikolay I., Krikunova, Ludmila I., Ivanova, Tatiana I., Salnikova, Lyubov E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Analysis Antioxidants Apolipoprotein E2 - genetics Apolipoproteins Body Mass Index Breast cancer Cancer Carcinoma Confidence intervals Deoxyribonucleic acid Diabetes Mellitus, Type 2 - epidemiology Disease DNA Endometrial cancer Endometrial Hyperplasia - genetics Endometrial Hyperplasia - pathology Endometrial Neoplasms - genetics Endometrial Neoplasms - pathology Female Gene Frequency Genes Genotype Gynecology Haplotypes Health risk assessment Hemochromatosis Protein Histocompatibility Antigens Class I - genetics Humans Hyperplasia Hypertension Hypertension - epidemiology Life expectancy Medical research Membrane Proteins - genetics Middle Aged Obesity Obstetrics Odds Ratio Oxidative stress Physiological aspects Polymorphism, Single Nucleotide Proteins State budgets Studies Women
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