Monocyte-Targeting Supramolecular Micellar Assemblies: A Molecular Diagnostic Tool for Atherosclerosis

Atherosclerosis is a multifactorial inflammatory disease that can progress silently for decades and result in myocardial infarction, stroke, and death. Diagnostic imaging technologies have made great strides to define the degree of atherosclerotic plaque burden through the severity of arterial steno...

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Veröffentlicht in:	Advanced healthcare materials 2015-02, Vol.4 (3), p.367-376
Hauptverfasser:	Chung, Eun Ji, Mlinar, Laurie B., Nord, Kathryn, Sugimoto, Matthew J., Wonder, Emily, Alenghat, Francis J., Fang, Yun, Tirrell, Matthew
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Apolipoproteins E - genetics Atherosclerosis Atherosclerosis - diagnosis Atherosclerosis - metabolism Atherosclerosis - pathology Binding Sites Chemokine CCL2 - chemistry Chemokine CCL2 - metabolism Chemokine CCL2 - pharmacokinetics Diagnostic software Diagnostic systems Drug Evaluation, Preclinical - methods Female Heart attacks Imaging Macrophages Mice, Transgenic Micelles molecular imaging Molecular Sequence Data Monocytes - metabolism Pathology, Molecular - methods peptide amphiphiles Peptides Progressions Receptors, CCR2 - metabolism Recombinant Proteins - genetics Recombinant Proteins - metabolism Recombinant Proteins - pharmacokinetics self-assembly targeting Tissue Distribution
Online-Zugang:	Volltext
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