Optimal Amount of Basic Fibroblast Growth Factor in Gelatin Sponges Incorporating β-Tricalcium Phosphate with Chondrocytes

Background: A gelatin sponge with slowly releasing basic fibroblast growth factor (b-FGF) enhances chondrogenesis. This study investigated the optimal amount of b-FGF in gelatin sponges to fabricate engineered cartilage. Materials and Methods: b-FGF (0, 10, 100, 500, 1000, and 2000 μg/cm 3 )-impregn...

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Veröffentlicht in:	Tissue engineering. Part A 2015-02, Vol.21 (3-4), p.627-636
Hauptverfasser:	Otani, Yushi, Komura, Makoto, Komura, Hiroko, Ishimaru, Tetsuya, Konishi, Kenichiro, Komuro, Hiroaki, Hoshi, Kazuto, Takato, Tsuyoshi, Tabata, Yasuhiko, Iwanaka, Tadashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatible Materials - chemical synthesis Calcium Phosphates - chemistry Cartilage, Articular - cytology Cartilage, Articular - growth & development Cells, Cultured Chondrocytes - cytology Chondrocytes - drug effects Chondrocytes - physiology Chondrogenesis - drug effects Chondrogenesis - physiology Delayed-Action Preparations - administration & dosage Delayed-Action Preparations - chemistry Dose-Response Relationship, Drug Equipment Design Equipment Failure Analysis Fibroblast Growth Factor 2 - administration & dosage Fibroblast Growth Factor 2 - chemistry Gelatin Sponge, Absorbable - chemistry Humans Materials Testing Original Original Articles Printing, Three-Dimensional Tissue Engineering - instrumentation Tissue Scaffolds
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