Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions

Systematic interrogation of mutation or protein modification data is important to identify sites with functional consequences and to deduce global consequences from large data sets. Mechismo (mechismo.russellab.org) enables simultaneous consideration of thousands of 3D structures and biomolecular in...

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Veröffentlicht in:	Nucleic acids research 2015-01, Vol.43 (2), p.e10-e10
Hauptverfasser:	Betts, Matthew J, Lu, Qianhao, Jiang, YingYing, Drusko, Armin, Wichmann, Oliver, Utz, Mathias, Valtierra-Gutiérrez, Ilse A, Schlesner, Matthias, Jaeger, Natalie, Jones, David T, Pfister, Stefan, Lichter, Peter, Eils, Roland, Siebert, Reiner, Bork, Peer, Apic, Gordana, Gavin, Anne-Claude, Russell, Robert B
Format:	Artikel
Sprache:	eng
Schlagworte:	Databases, Protein High-Throughput Nucleotide Sequencing Humans Methods Online Mutation Neoplasms - genetics Protein Conformation Protein Interaction Mapping Proteins - genetics Proteomics
Online-Zugang:	Volltext
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