Low-cost blast wave generator for studies of hearing loss and brain injury: Blast wave effects in closed spaces

•Many devices used in animal models of blast wave exposure are large and expensive.•We developed a low cost blast wave generator easily housed in laboratory settings.•The generator reliably produced blasts with peak pressures of up to 198dB SPL (159.4kPa).•Exposure of rats to blast waves caused dama...

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Veröffentlicht in:	Journal of neuroscience methods 2015-03, Vol.242, p.82-92
Hauptverfasser:	Newman, Andrew J., Hayes, Sarah H., Rao, Abhiram S., Allman, Brian L., Manohar, Senthilvelan, Ding, Dalian, Stolzberg, Daniel, Lobarinas, Edward, Mollendorf, Joseph C., Salvi, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blast Injuries - complications Blast Injuries - pathology Blast Injuries - physiopathology Blast wave generator Brain Injuries - etiology Brain Injuries - pathology Brain Injuries - physiopathology Cochlea - injuries Cochlea - pathology Cochlea - physiopathology Cochlear hair cells Disease Models, Animal Equipment and Supplies - economics Equipment Design Hearing loss Hearing Loss - etiology Hearing Loss - pathology Hearing Loss - physiopathology Hippocampal neurogenesis Hippocampus - injuries Hippocampus - pathology Hippocampus - physiopathology Low cost Neurogenesis - physiology Otoacoustic Emissions, Spontaneous - physiology Pressure - adverse effects Rats, Sprague-Dawley Traumatic brain injury
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