Opposing effects of oxytocin on overt compliance and lasting changes to memory
From infancy we learn to comply with societal norms. However, overt compliance is not necessarily accompanied by a change in internal beliefs. The neuromodulatory processes underlying these different phenomena are not yet understood. Here, we test the role of oxytocin in controlling overt compliance...
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| Veröffentlicht in: | Neuropsychopharmacology (New York, N.Y.) N.Y.), 2015-03, Vol.40 (4), p.966-973 |
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| container_title | Neuropsychopharmacology (New York, N.Y.) |
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| creator | Edelson, Micah G Shemesh, Maya Weizman, Abraham Yariv, Shahak Sharot, Tali Dudai, Yadin |
| description | From infancy we learn to comply with societal norms. However, overt compliance is not necessarily accompanied by a change in internal beliefs. The neuromodulatory processes underlying these different phenomena are not yet understood. Here, we test the role of oxytocin in controlling overt compliance versus internalization of information delivered by a social source. After intranasal oxytocin administration, participants showed enhanced compliance to the erroneous opinion of others. However, this expression was coupled with a decrease in the influence of others on long-term memories. Our data suggest that this dissociation may result from reduced conflict in the face of social pressure, which increases immediate conforming behavior, but reduces processing required for deep encoding. These findings reveal a neurobiological control system that oppositely affects internalization and overt compliance. |
| doi_str_mv | 10.1038/npp.2014.273 |
| format | Article |
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| subjects | Administration, Intranasal Adult Association Learning - drug effects Choice Behavior - drug effects Compliance Compliance - drug effects Conformity Cross-Over Studies Hormones Humans Influence Male Memory Memory - drug effects Memory, Long-Term - drug effects Neurobiology Neuropsychological Tests Neurosciences Original Oxytocin - administration & dosage Single-Blind Method Social Behavior |
| title | Opposing effects of oxytocin on overt compliance and lasting changes to memory |
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