BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

Genomic structural variation (SV), a common hallmark of cancer, has important predictive and therapeutic implications. However, accurately detecting SV using high-throughput sequencing data remains challenging, especially for 'targeted' resequencing efforts. This is critically important in...

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Veröffentlicht in:	Nucleic acids research 2015-02, Vol.43 (3), p.e19-e19
Hauptverfasser:	Abo, Ryan P, Ducar, Matthew, Garcia, Elizabeth P, Thorner, Aaron R, Rojas-Rudilla, Vanesa, Lin, Ling, Sholl, Lynette M, Hahn, William C, Meyerson, Matthew, Lindeman, Neal I, Van Hummelen, Paul, MacConaill, Laura E
Format:	Artikel
Sprache:	eng
Schlagworte:	Biopsy Humans Methods Online Mutation Neoplasms - genetics Neoplasms - pathology Nucleic Acids - chemistry Nucleic Acids - genetics Sequence Analysis
Online-Zugang:	Volltext
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