Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: From ferroptosis to stroke

Neurologic conditions including stroke, Alzheimer disease, Parkinson disease, and Huntington disease are leading causes of death and long-term disability in the United States, and efforts to develop novel therapeutics for these conditions have historically had poor success in translating from bench...

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Veröffentlicht in:Free radical biology & medicine 2013-09, Vol.62, p.26-36
Hauptverfasser: Speer, Rachel E., Karuppagounder, Saravanan S., Basso, Manuela, Sleiman, Sama F., Kumar, Amit, Brand, David, Smirnova, Natalya, Gazaryan, Irina, Khim, Soah J., Ratan, Rajiv R.
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